Luce S

Math and Science Teacher

Fusion Academy

Dec 2025 - Present • 5 mos

● Deliver rigorous, individualized 1:1 instruction in advanced mathematics and science, including Algebra, Geometry, Chemistry, and Trigonometry ● Apply quantitative modeling, statistical reasoning, and data interpretation frameworks to strengthen analytical problem-solving skills ● Translate complex scientific and mathematical concepts into structured, systems-based thinking approaches grounded in real-world STEM applications ● Design differentiated lesson plans aligned with state standards while accelerating advanced learners and supporting students requiring targeted intervention ● Adapt instructional strategies and learning plans to support students with diverse learning differences, implementing structured scaffolding, multi-modal teaching approaches, and individualized pacing to ensure mastery and sustained success ● Cultivate executive functioning, scientific reasoning, and hypothesis-driven thinking within students to prepare them for the future ● Leverage technology and data-driven instructional tools to monitor performance trends and guide continuous improvement

Scientist

Bristol Myers Squibb • Full time

Jan 2024 - Mar 2025 • 1 yr 2 mos

● Established and maintained ex vivo human organoid cultures derived from pancreatic ductal adenocarcinoma (PDAC), non-small cell lung adenocarcinoma (NSCLC), and colorectal adenocarcinoma (CRC) patients from PDX or human specimens ● Managed a working organoid biobank including reagent inventory and supply ordering and implemented a standardized workflow including quality control, biobanking, characterization, propagation, and derivatization ● Optimized and adapted workflow processes and culture conditions to maximize model success ● Utilized plate-based 384-well cellular assays to support precision discovery and translational research efforts with both organoid and 2D cell culture models ● Acted as a point-of-contact within oncology for organoid model cultures and communicate findings to fellow colleagues ● Set up a fully functional, dedicated lab space for organoid work within my department

Research Technician II

Cold Spring Harbor Laboratory • Full time

Aug 2020 - Dec 2023 • 3 yrs 4 mos

● Established and maintained human organoid cultures from pancreatic ductal adenocarcinoma (PDAC) patient tissue ● Co-managed a working organoid biobank with responsibilities including reagent inventory, cryopreservation of material, and characterization of models ● Collaborated with institutions including Northwell Health and University of Toronto Cancer Centre on PASS-01 clinical trial (NCT04469556) to implement organoids in precision medicine ● Ran high throughput drug screens (384 and 1536-well) and proteomics/metabolomics assays to better assess how to approach PDAC diagnostics, treatment, and biology ● Organized organoid biobank via clinical database barcoding system ● Trained scientists interested in implementing organoid culture in their respective labs/universities across the United States ● Derived ~200 PDAC organoid models during tenure, about 20% of the Organoid Core biobank as of November 2023, maintaining 20-30 lines simultaneously in culture ● Contributed data, methodology development, and written content to publications (Demyan, et al.) and other manuscripts in preparation ● Supervisors: Dennis Plenker, PhD and Amber Habowski, PhD